American Life Sciences Pharmaceuticals, Inc.

ALSP Inc. (American Life Science Pharmaceuticals, Inc.), is a privately held company based in San Diego, California, developing small molecule drugs for treating neurodegenerative diseases, initially focused on Alzheimer’s disease and traumatic brain injury (TBI). Their approach is to identify key enzymes in the brain, called neuroproteases that produce biologically active peptides that are thought to cause the disease. They then use those enzymes as targets for screening compounds that inhibit the neuroproteases, and thereby reduce production of the harmful peptides, to treat the disease. By using this well-established process, they have identified a family of drugs that is highly effective at reversing the symptoms of Alzheimer’s and TBI in animal models of the disease. They are advancing their lead compound into clinical trials and continuing their search for additional drugs to treat Alzheimer’s and other devastating neurodegenerative diseases. See